Inheritance+Pattern+of+SMA

Inheritance Patter of SMA

SMA is an X linked disorder which is different than sex-linked disorders. (Spinal Muscular Atrophy) X linked disorders effect mostly males. Mutations that cause this disorder and other disorders can be passed down through generations of a family. A woman can be a carrier of the disorder which means she has history of the disorder in her family, but she does not have the disorder. This means the gene is recessive in her DNA, but it can still be passed down to children. Each son of a female carrier has a 50% chance of having the disorder. In order to have the disorder you must have two copies of the recessive gene.(About X linked disorders)